Flumequine
Catalog No.
B2292
DNA topoisomerase II inhibitor，synthetic chemotherapeutic antibiotic
Featured Products
Flumequine (CAS: 42835-25-6) is a small-molecule inhibitor targeting DNA topoisomerase II.
Flumequine exerts its biological activity primarily through inhibition of DNA topoisomerase II, thereby interfering with DNA replication and transcriptional processes. Flumequine demonstrates inhibitory activity, with an IC50 value of approximately 15 μM.
Based on these pharmacological properties, Flumequine holds research potential in studies of DNA replication dynamics, enzyme inhibition, and screening of therapeutic strategies in cancer research involving topoisomerase II modulation.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 261.25 |
| Cas No. | 42835-25-6 |
| Formula | C14H12FNO3 |
| Synonyms | R-802 |
| Solubility | insoluble in EtOH; insoluble in H2O; ≥9.35 mg/mL in DMSO |
| Chemical Name | 9-fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid |
| SDF | Download SDF |
| Canonical SMILES | CC(CCc1cc(F)c2)N(C=C3C(O)=O)c1c2C3=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
