Pefloxacin Mesylate
Pefloxacin Mesylate (CAS: 70458-95-6) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II).
Pefloxacin Mesylate exerts its biological activity primarily through inhibition of DNA gyrase, thereby interfering with DNA replication and transcription. In biochemical research assays, Pefloxacin Mesylate demonstrates inhibitory activity, with IC50 values in vitro in the low micromolar range depending on bacterial species and assay conditions.
Based on these pharmacological properties, Pefloxacin Mesylate holds research potential in microbiological assays, antimicrobial susceptibility tests, and studies of bacterial enzyme inhibition
.| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 429.46 |
| Cas No. | 70458-95-6 |
| Formula | C18H24FN3O6S |
| Solubility | insoluble in EtOH; ≥53.5 mg/mL in H2O; ≥6.83 mg/mL in DMSO |
| Chemical Name | 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid |
| SDF | Download SDF |
| Canonical SMILES | CCN(C=C(C(O)=O)C(c1c2)=O)c1cc(N1CCN(C)CC1)c2F.CS(O)(=O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure








