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Etravirine (TMC125)

In stock
Catalog No.
B2224
Reverse transcriptase inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$85.00
In stock
10mg
$70.00
In stock
50mg
$260.00
In stock
1g
$980.00
In stock

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Background

Etravirine (R165335; TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt435.28
Cas No.269055-15-4
FormulaC20H15BrN6O
Solubility≥19.35mg/mL in DMSO
Chemical Name4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile
SDFDownload SDF
Canonical SMILESCC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Chemical structure

Etravirine (TMC125)