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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B6009 6-Thio-dG

Summary: telomere disrupting compound

≥12.67 mg/mL
B6010 Coelenterazine

Summary: luminescent enzyme substrate

≥42.3 mg/mL
B6011 A-1210477
2 Citation

Target: Mcl-1

Summary: MCL-1 inhibitor

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B6012 Pexmetinib (ARRY-614)

Target: p38|Tie-2

Summary: dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase

insoluble in H2O; ≥107.6 mg/mL
B6013 AMG319

Summary: PI3Kδ inhibitor

Soluble in DMSO
B6014 BI-847325

Summary: dual inhibitor of MEK and Aurora kinases

≥24.1 mg/mL
B6018 Disodium (R)-2-Hydroxyglutarate

Summary: inhibitor of α-ketoglutarate-dependent dioxygenases

insoluble in EtOH; insoluble in DMSO; ≥9.1 mg/mL
B6019 Sodium Tauroursodeoxycholate (TUDC)

Target: BCPCF efflux

Summary: water soluble bile salt

≥26.1 mg/mL
B6020 GSK621
1 Citation

Target: AMPK

Summary: AMPK agonist

insoluble in H2O; insoluble in EtOH; ≥28.5 mg/mL
B6021 Dp44mT

Summary: iron chelator and anticancer agent

≥62.5 mg/mL