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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B5929 Decernotinib(VX-509)

Summary: Selective and orally active JAK3 inhibitor

insoluble in H2O; ≥16.95 mg/mL
B5930 mavatrep

Summary: TRPV1 antagonist

Soluble in DMSO
B5935 TBA354

Summary: New antitubercular agent

insoluble in EtOH; insoluble in H2O; ≥17.6 mg/mL
B5936 ACY-241

Summary: Selective and orally active HDAC6 inhibitor

≥23.4 mg/mL
B5937 KPT-9274

Summary: Orally acitve allosteric inhibitor of PAK4

≥22.45 mg/mL
B5940 TP-0903

Target: AXL

Summary: AXL receptor tyrosine kinase inhibitor, anti-cancer agent

≥25.8 mg/mL
B5941 ONO-4059

Summary: Highly potent and selective oral Btk inhibitor

Soluble in DMSO
B5942 AS601245

Summary: c-Jun NH2-terminal protein kinase inhibitor

insoluble in H2O; insoluble in EtOH; ≥14.25 mg/mL
B5944 Carteolol HCl

Summary: Non-selective beta-adrenoceptor antagonist

insoluble in EtOH; ≥16.44 mg/mL
B5946 EW-7197
1 Citation

Target: BMP and Other Activin Receptors

Summary: Selective inhibitor of TGF-β type I receptor kinase

≥39.9 mg/mL