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Bioactive Compounds
Signaling Pathways

Signaling Pathways

B5822 TMC647055 Choline salt

Summary: inhibitor of the hepatitis C virus NS5B polymerase

insoluble in H2O; insoluble in EtOH; ≥72.8 mg/mL
B5823 LP533401 hcl

Target: Tph

Summary: Tph-1 inhibitor

≥56.3 mg/mL
B5830 G007-LK
1 Citation

Summary: tankyrase 1/2 inhibitor

≥26.5 mg/mL
B5831 Acalisib (GS-9820)

Target: PI3K

Summary: PI3Kδ inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
B5832 Altiratinib
1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
B5833 GSK503
2 Citation

Summary: EZH2 inhibitor

≥21.65 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO
B5836 AZ5104

Target: EGFR

Summary: EGFR inhibitor

insoluble in H2O; ≥16.95 mg/mL
B5838 BX517(PDK1 inhibitor2)

Summary: PDK1 inhibitor

insoluble in H2O; insoluble in EtOH; ≥8.55 mg/mL
B5839 SU6656

Target: Src|Lyn|YES|Fyn

Summary: Src tyrosine kinases inhibitor

insoluble in H2O; insoluble in EtOH; ≥18.55 mg/mL