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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8893 Rucaparib (free base)

Target: PARP

Summary: Potent PARP inhibitor

insoluble in H2O; insoluble in EtOH; ≥16.15 mg/mL
A8890 HTH-01-015

Target: NUAK

Summary: NUAK1 inhibitor,highly specific and selective

≥23.45 mg/mL
B8000 GNE-493

Summary: Pan-PI3K/mTOR inhibitor

Soluble in DMSO
B8001 GNE-477

Summary: dual PI3K/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL
B8002 LY2857785

Summary: CDK9 inhibitor
B8003 WH-4-023

Summary: Lck/Src inhibitor,potent and selective

≥56.9 mg/mL
B8006 c-di-AMP

Summary: bacterial secondary messenger

Soluble in DMSO
B8009 UNC0379

Summary: N-lysine methyltransferase SETD8 inhibitor

≥49.7 mg/mL
B8010 NIBR189

Summary: EBI2 (GPR183) receptor antagonist

≥42.9 mg/mL
B8014 ML355

Summary: 12-LOX inhibitor

≥42.7 mg/mL