SB-747651A dihydrochloride
Catalog No.
A9983
A potent ATP-competitive mitogen and stress-activated kinase 1 (MSK1) inhibitor
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SB-747651A dihydrochloride is a potent ATP-competitive mitogen and stress-activated kinase 1 (MSK1) inhibitor with an IC50 value of 11 nM. MSK1, a serine/threonine protein kinase, is involved in intracellular signal transduction pathways and regulates important physiological processes such as inflammation, cell proliferation and gene expression. SB-747651A dihydrochloride inhibits kinase activity of MSK1 by competitively binding ATP-binding sites, thus blocking activation of downstream signaling pathways. The compound has potential therapeutic applications in the study of inflammation, cancer and neurodegenerative diseases.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 415.32 |
| Cas No. | 1781882-72-1 |
| Formula | C16H24Cl2N8O |
| Solubility | Soluble in DMSO |
| Chemical Name | 4-(1-ethyl-7-((piperidin-4-ylamino)methyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride |
| SDF | Download SDF |
| Canonical SMILES | CCN1C(C2=NON=C2N)=NC3=C1C(CNC4CCNCC4)=CN=C3.Cl.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
