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Search results for: 'gdc 0349'

Search results for: 'gdc 0349'

A8210 GDC-0941
10 Citation

Target: PI3K

Summary: PI3K inhibitor,potent and selective

≥25.7 mg/mL
A4224 GDC-0152
2 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: IAP antagonist,potent amd samll-molecule

≥24.95 mg/mL
A3021 GDC-0449 (Vismodegib)
1 Citation

Target: P-glycoprotein (P-gp)|Hedgehog

Summary: Hedgehog antagonist,potent and selective

≥21.08 mg/mL
BA3639 GDC-0349

Summary: GDC-0349 is a potent, ATP-competitive and selective inhibitor.
A5071 GDC-0879
1 Citation

Target: Raf

Summary: B-Raf inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
B5817 GDC-0994
2 Citation

Summary: ERK1/2 inhibitor

≥44.1 mg/mL
A3432 GDC-0941 dimethanesulfonate

Summary: PI3K inhibitor

insoluble in H2O; insoluble in EtOH; ≥207.6 mg/mL
A3637 GDC-mTOR inhibitor

Summary: MTOR inhibitor

Soluble in DMSO
B1047 GDC-0032

Target: PI3K

Summary: PI3Kα inhibitor

≥23.05 mg/mL
B1135 GDC-0623

Target: MEK

Summary: MEK1 inhibitor, potent and ATP-uncompetitive

insoluble in H2O; ≥16.85 mg/mL