Signaling pathways
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C8414 CM398Summary: CM398 is a highly selective - C8415 CZ415Summary: CZ415 is a potent and highly selective inhibitor.
- C8416 II-B08Summary: II-B08 is a reversible and noncompetitive inhibitor (5.5 μM, 15.7, and 14.3 μM for SHP2, SHP1, and PTP1B, respectively).
- C8417 hVEGF-IN-2Summary: hVEGF-IN-2 is a selective (Flk-1) receptor tyrosine kinase inhibitor.
- C8418 SU5208Summary: Inhibits vascular endothelial growth factor receptor 2.
- C8419 VicatertideSummary: An inhibitor.
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A9084 4-Thiazolecarboxylic acidSummary: NCATS-SM1441 (compound 52) is a lactate dehydrogenase (LDH) inhibitor (IC50=40 nM). By inhibiting the activity of LDH, NCATS-SM1441 is able to reduce the production of lactic acid in cancer cells, helping to slow or stop the proliferation of cancer cells. -
A9086 Naphthol AS-MX phosphateSummary: Naphthol AS-MX phosphate is a synthetic naphthol dye that is used in the diagnosis of infectious diseases, such as Klebsiella aerogenes. -
A9087 alpha-SpinasterolSummary: α-Spinasterol is an orally taken antagonist of transient receptor potential vanilloid 1 ( TRPV1), and it's also an inhibitor of COX-1 and COX-2. -
A9918 CurdlanSummary: A polysaccharide produced by bacteria