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Biochemical Reagent
Signaling pathways

Signaling pathways

BA5571 VU6012962

Summary: VU6012962 is an orally bioavailable, CNS-permeable, metabotropic glutamate receptor 7-negative modifier of mutations (NAM).
BA5572 AZD-8529

Summary: AZD-8529 is an effective.
BA5573 Decoglurant

Summary: Decoglurant (RO4995819) is a negative variational modulator.
BA5574 LY487379

Summary: LY487379 is a selective human orthomolecular modulator (PAM).
BA5575 ABP688

Summary: ABP688 is a high affinity antagonist.
BA5576 Methoxy-PEPy

Summary: Methoxy-PEPy is a highly potent and selective inhibitor of the mGlu5 receptor.
BA5577 HTL14242

Summary: HTL14242 (HTL0014242) is an advanced, orally active negatively variable modulator with summed values of 9.3 and 9.2, respectively.
BA5578 FPTQ

Summary: FPTQ is a potent antagonist with inhibitory values of 6 nM and 1.4 nM in human and mouse, respectively.
BA5579 JNJ-46281222

Summary: JNJ-46281222 is a selective metabolic glutamate 2 efficient PAM (orthosteric modifier).
BA5580 FTIDC

Summary: FTIDC is an oral, non-competitive, selective metabotropic glutamate receptor 1 antagonist.