Signaling pathways
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BA5261 CCX354Summary: CCX354 is a potent antagonist. -
BA5262 CKLF1-C27Summary: CKLF1-C27 is a C-terminal peptide of CKLF1 that binds to the receptor and activates the pathway. -
BA5263 Ubrogepant -
BA5264 AtogepantSummary: Atogepant (MK-8031) is an orally effective and selective antagonist. -
BA5265 CagrilintideSummary: Cagrilintide is a novel long-acting acylated glucagon analog under investigation as a non-selective agonist of the amylin receptor (AMYR) and calcitonin G protein-coupled receptor (CTR). -
BA5266 VazegepantSummary: Vazegepant (Zavegepant) is an orally effective calcitonin gene-related peptide receptor antagonist with potential for acute studies in migraine. -
BA5267 ChemR23-IN-1Summary: ChemR23-IN-1 is an inhibitor at 38 nM and 100 nM for human and mouse, respectively. -
BA5268 PentagastrinSummary: Pentagastrin (ICI-50123) is a potent and selective cholecystokinin B receptor antagonist. -
BA5269 DevazepideSummary: Devazepide (L-364,718) is a potent, competitive, selective, orally available, nonpeptide cholecystokinin receptor antagonist with values of 81pM, 45pM and 245nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively. -
BA5271 SograzepideSummary: Sograzepide (Netazepide; YF476; YM-220) is a very potent, highly selective and orally active antagonist.
