Signaling pathways
-
BA2790 UZH1aSummary: UZH1a is a potent and selective inhibitor. - BA2791 DC661Summary: DC661 is a potent inhibitor of palmitoyl protein thioesterase 1, inhibits autophagy, and acts as an anti-lysosomal agent.
- BA2792 EldecalcitolSummary: Eldecalcitol (ED-71) is an orally active vitamin D3 analog that inhibits bone resorption and increases bone density.
- BA2793 9-ING-41Summary: 9-ING-41 (Elraglusib) is a maleimide-based ATP-competitive and selective inhibitor of glycogen synthase kinase-3β.
- BA2794 ON1231320Summary: ON1231320 is a highly specific polo-like kinase 2 inhibitor.
- BA2795 1G244Summary: 1G244 was a potent inhibitor at 12 nM and 84 nM, respectively, but did not inhibit DPPIV and DPPII.
- BA2796 FlunisolideSummary: Flunisolide is a corticosteroid, an orally active glucocorticoid receptor activator with anti-inflammatory activity.
- BA2797 STAT3-IN-1Summary: STAT3-IN-1 is a potent, selective, and orally effective inhibitor with values of 1.82 μM and 2.14 μM in HT29 and MDA-MB231 cells, respectively.
- BA2798 TM5441Summary: TM5441, an orally bioavailable inhibitor of fibrinogen activator inhibitor-1, inhibited several cancer cell lines with values ranging from 13.9 to 51.1 μM and induced intrinsic cell death in several human cancer cells.
- BA2799 SilybinSummary: Silybin is a flavin oligosaccharide isolated from grass thistle seeds.