Signaling pathways
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BA5409 JNJ-39758979Summary: JNJ-39758979 is a selective, orally active, high affinity histamine H receptor antagonist with values of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H receptors, respectively. - BA5410 CarebastineSummary: Carebastine is the active metabolite of Ebastine.
- BA5411 CyclizineSummary: Cyclizine, a piperazine derivative, is a potent and selective histamine receptor antagonist.
- BA5412 EnerisantSummary: Enerisant (TS-091) is a potent, highly selective, competitive and orally active receptor antagonist/inverse agonist.
- BA5414 FexofenadineSummary: Fexofenadine (MDL-16455) is an orally active and non-sedating receptor antagonist.
- BA5415 SamelisantSummary: Samelisant (SUVN-G3031) is an orally effective, selective histamine H3 receptor (H3R) inverse agonist that crosses the blood-brain barrier.
- BA5416 Antihistamine-1Summary: Antihistamine-1 is an H1-antihistamine capable of penetrating the blood-brain barrier (=6.9 nM).
- BA5417 ToreforantSummary: Toreforant is a potent and selective antagonist of the histamine H4 receptor.
- BA5418 DiphenylpyralineSummary: Diphenylpyraline is a potent antagonist of histamine H1 receptors.
- BA5419 NiaprazineSummary: Niaprazine is a histamine H1 receptor antagonist.