Signaling pathways
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BA5032 GentiseinSummary: Mangiferin, the major metabolite of Gentisein (NSC329491), showed the most potent 5-HT uptake inhibition - BA5033 l-PindololSummary: l-Pindolol ((-)-pindolol) is a reversible, competitive, orally active antagonist.
- BA5034 FlumexadolSummary: Flumexadol is a selective and affinity receptor agonist.
- BA5035 DonitriptanSummary: Donitriptan is a potent high affinity receptor agonist.
- BA5036 S-15535Summary: S-15535 is a receptor ligand with high selectivity.
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BA5037 PipamperoneSummary: Pipamperone (Floropipamide; McN-JR3345; R3345) is a high affinity antagonist of both the receptor (=8.2) and the receptor (=8.0). - BA5038 RenzaprideSummary: Renzapride (BRL24924) is a substituted benzamide that is a receptor agonist.
- BA5039 AdoprazineSummary: Adoprazine (SLV313) is a full agonist at the receptor.
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BA5040 LumateperoneSummary: Lumateperone (ITI-007) is an orally active receptor antagonist (Ki=0.54nM) - BA5041 DothiepinSummary: Dothiepin (Dosulepin; Dothep) is an antidepressant with sedative/anxiolytic activity.