Signaling pathways
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BA8826 PCI-33380Summary: A selective, irreversible inhibitor (fluorescent probe) of Bruton's tyrosine kinase. - BA8827 TL-895Summary: TL-895 is a potent, orally active, ATP-competitive, highly selective irreversible inhibitor with summed values of 1.5 nM and 11.9 nM, respectively.
- BA8828 BIIB091Summary: BIIB091 is a potent, selective, orally active and reversible inhibitor with values <0.5 nM.
- BA8829 CNX-500Summary: CNX-500 is a probe consisting of a covalent inhibitor (CC-292) chemically linked to biotin.
- BA8831 BLK-IN-2Summary: BLK-IN-2 is a potent, selective and irreversible inhibitor of B-lymphotyrosine kinase.
- BA8832 ElsubrutinibSummary: Elsubrutinib (ABBV-105) is an orally active, potent, selective and irreversible inhibitor of Bruton'styrosinekinase.
- BA8833 GBD-9Summary: GBD-9 is a two-mechanism degrader that effectively degrades and by recruiting E3 ligases.
- BA8834 BIIB068Summary: BIIB068 is a potent, selective, reversible and orally active inhibitor.
- BA8835 TAK-020Summary: TAK-020 is a covalent inhibitor.
- BA8836 BMS-986142Summary: BMS-986142 is a potent and highly selective reversible inhibitor.