Signaling pathways
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BA5560 JNJ-46778212Summary: JNJ-46778212 (VU0409551) is an orthotropic modifier. -
BA5561 RO0711401Summary: RO0711401 is a selective orthosteric modulator of receptors with oral activity. -
BA5562 VU0650786Summary: VU0650786 is a potent, CNS-transmitting, selective glutamate receptor subtype 3 negative modulator. -
BA5563 BMS-984923Summary: BMS-984923 is a potent silent allosteric modulator with good affinity (K=0.6nM), good oral bioavailability and blood-brain barrier permeability. -
BA5564 VU6005649Summary: A CNS-permeable receptor agonist. -
BA5565 ADX88178Summary: ADX88178 is a potent metabotropic glutamate receptor 4 orthosteric modulator (PAM). -
BA5566 VU0422288Summary: VU0422288 (ML396) is an orthosteric modulator of the type III mGlu receptor (mGlus). -
BA5567 JNJ-42153605Summary: JNJ-42153605 is an orthosteric modulator of the metabotropic glutamate 2 receptor. -
BA5568 FITMSummary: FITM is a negatively-mutated modulator of the receptor. -
BA5569 CVN636Summary: CVN636 is an orally effective selective variable agonist.

