Signaling pathways
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BA6384 MS9449Summary: MS9449 was an effective degrader with 17 nM and 10 nM for wild-type and mutant L858R, respectively. - BA6385 SDZ281-977Summary: Derivatives of the receptor tyrosine kinase inhibitor LavendustinA.
- BA6386 BGB-102Summary: Multi-kinase inhibitors.
- BA6387 EMI56Summary: EMI56 is a derivative of EMI1, and EMI56 is more potent than EMI1 against mutant phenotypes.
- BA6388 EMI48Summary: EMI48 is a derivative of EMI1, and EMI48 has greater potency against mutant phenotypes than EMI1.
- BA6389 CHMFL-EGFR-202Summary: CHMFL-EGFR-202 is a potent, irreversible inhibitor of the epidermal growth factor receptor mutant kinase.
- BA6392 EGFR-IN-9Summary: EGFR-IN-9 is a potent inhibitor with 7nM and 28nM for wild-type and double mutant kinases (L858R/T790M), respectively.
- BA6393 MS154Summary: MS154 is a first-in-class E3 ligase recruiting degrader.
- BA6394 EGFR-IN-5Summary: An inhibitor.
- BA6395 TP-3654Summary: TP-3654 is a second generation kinase inhibitor.