Biochemical Reagent
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BA9130 Super-TDUSummary: Super-TDU is a specific antagonist that targets the YAP-TEAD interaction. - BA9131 VT02956Summary: VT02956 is an inhibitor (0.76 nM for LATS1 and 0.52 nM for LATS2).
- BA9132 YAP-TEAD-IN-2Summary: YAP-TEAD-IN-2 is a potent (protein-protein interaction) inhibitor.
- BA9133 TEAD-IN-2Summary: TEAD-IN-2 is a novel active inhibitor with oral activity that regulates the transcription enhancer-associated structural domain (TEAD) by ubiquitination and/or compound degradation.
- BA9134 DC-TEADin02Summary: DC-TEADin02 is a potent inhibitor of TEAD self-palmitoylation.
- BA9135 SWTX-143Summary: SWTX-143 is a novel covalent/TAZ-TEAD inhibitor that binds to the palmitoylated pocket of all four TEAD isoforms.
- BA9136 LM-41Summary: LM-41 is a Flufenamicacid-derived inhibitor that strongly reduces the expression of CTGF, Cyr61, Axl and NF2.
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BA9137 LF3Summary: LF3 is an interacting antagonist with antitumor activity. - BA9138 TegatrabetanSummary: Tegatrabetan (BC2059) is an antagonist.
- BA9139 ZW4864Summary: ZW4864 is an orally active and selective inhibitor of βcatenin/B-Celllymphoma9 protein-protein interactions.