Biochemical Reagent
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BA7810 MersalylSummary: Mersalyl (Salirgan) is a potent inducer of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1). - BA7811 VHL-IN-1Summary: VHL-IN-1 is an inhibitor of the ubiquitin E3 ligase vonHippel-Lindau (VHL) (dissociation constant Kd=37nM) that stabilizes and induces HIF-1α transcriptional activity.
- BA7812 THS-044Summary: Binds and stabilizes the HIF2αPAS-B folding state and regulates HIF2 activity.
- BA7813 HIF1-IN-3Summary: HIF1-IN-3 is a potent inhibitor.
- BA7814 GSK360ASummary: GSK360A is an orally active inhibitor with values of 10, 100 and 126 nM for PHD1, PHD2 and PHD3, respectively.
- BA7815 HIF-PHD-IN-1Summary: HIF-PHD-IN-1 is an orally active inhibitor of the structural domain of the hypoxia-inducible factor prolyl hydroxylase.
- BA7816 ZINC13466751Summary: ZINC13466751 is a potent inhibitor of the interaction.
- BA7817 HIF-1α-IN-5Summary: HIF-1α-IN-5 is an inhibitor.
- BA7818 HIF-2α-IN-3Summary: HIF-2α-IN-3 is a variant inhibitor.
- BA7819 TM6089Summary: TM6089 is a unique inhibitor that stimulates activity without iron chelation, induces angiogenesis and exerts a protective effect on ischemic organs.