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Biochemical Reagent

Biochemical Reagent

BA5661 Danavorexton

Summary: Danavorexton (TAK-925) is a cerebropermeable agonist of the orexin receptor.
BA5662 Seltorexant

Summary: Seltorexant (JNJ-42847922) is an orally active, high affinity and selective orexin-2 receptor antagonist.
BA5663 MK-1064

Summary: MK-1064 is a selective, orally active antagonist (0.5nM,:18nM).
BA5664 SB-649868

Summary: SB-649868 is an orally effective selective orexin and receptor antagonist.
BA5665 Firazorexton

Summary: Firazorexton (TAK-994freebase) is an orally active, brain-permeable orexin type 2 receptor agonist.
BA5666 YNT-185

Summary: YNT-185 is a non-peptide, selective orexin type 2 receptor agonist.
BA5667 ACT-462206

Summary: ACT-462206 is an orally effective dual/receptor antagonist at 60nM and 11nM, respectively.
BA5668 Vornorexant

Summary: Vornorexant (ORN-0829; TS-142) is a potent dual antagonist.
BA5669 RTIOXA-43

Summary: RTIOXA-43 is an orexin receptor agonist.
BA5670 MK-3697

Summary: MK-3697 is a potent and selective antagonist of the OX2 receptor.