Biochemical Reagent
-
BA2651 MC-SN38Summary: MC-SN38 is an active molecular coupler consisting of SN38, a potent microtubule disruptor, and a non-cleavable MClinker for the synthesis of antibody active molecular couplers (ADCs). - BA2652 MMAE-SMCCSummary: MMAE-SMCC is an antibody-coupled active molecule consisting of MMAE, a potent inhibitor of mitotic and microtubule proteins, and SMCC, a connector.
- BA2653 endo-BCN-PEG4-Val-Cit-PAB-MMAESummary: endo-BCN-PEG4-Val-Cit-PAB-MMAE can be used to synthesize antibody-coupled active molecules (ADCs).
- BA2654 Lys-SMCC-DM1Summary: Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a coupler that inhibits microtubule protein polymerization.
- BA2656 SuO-Glu-Val-Cit-PAB-MMAESummary: SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists of degradable (cleavable) (SuO-Glu-Val-Cit-PAB) and MMAE, which is a potent microtubule (tubulin) inhibitor.
- BA2657 OSu-PEG4-VC-PAB-MMAESummary: OSu-PEG4-VC-PAB-MMAE was involved in the synthesis of GDP-FAmPMMAE (methyl auristatin E).
- BA2658 SC-VC-PAB-MMAESummary: SC-VC-PAB-MMAE is part of an antibody-coupled active molecule.
- BA2659 SPBSummary: SPB is the active molecular linker of ADC.
- BA2660 MCC-DM1Summary: MCC-DM1 is used as an active molecule-linker coupler for ADC synthesis, e.g. for the synthesis of Anti-CD22-MCC-DM1.
- BA2661 SN38-COOHSummary: SN38-COOH can be used to synthesize antibody-activated molecule couplings (ADCs).