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Biochemical Reagent

Biochemical Reagent

BA2651 MC-SN38

Summary: MC-SN38 is an active molecular coupler consisting of SN38, a potent microtubule disruptor, and a non-cleavable MClinker for the synthesis of antibody active molecular couplers (ADCs).
BA2652 MMAE-SMCC

Summary: MMAE-SMCC is an antibody-coupled active molecule consisting of MMAE, a potent inhibitor of mitotic and microtubule proteins, and SMCC, a connector.
BA2653 endo-BCN-PEG4-Val-Cit-PAB-MMAE

Summary: endo-BCN-PEG4-Val-Cit-PAB-MMAE can be used to synthesize antibody-coupled active molecules (ADCs).
BA2654 Lys-SMCC-DM1

Summary: Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a coupler that inhibits microtubule protein polymerization.
BA2656 SuO-Glu-Val-Cit-PAB-MMAE

Summary: SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists of degradable (cleavable) (SuO-Glu-Val-Cit-PAB) and MMAE, which is a potent microtubule (tubulin) inhibitor.
BA2657 OSu-PEG4-VC-PAB-MMAE

Summary: OSu-PEG4-VC-PAB-MMAE was involved in the synthesis of GDP-FAmPMMAE (methyl auristatin E).
BA2658 SC-VC-PAB-MMAE

Summary: SC-VC-PAB-MMAE is part of an antibody-coupled active molecule.
BA2659 SPB

Summary: An agent-linker conjugate for antibody-drug conjugates (ADC) that contains the anti-inflammatory agent Xanthotoxol linked via an ADC linker

≥3.88 mg/mL
BA2660 MCC-DM1

Summary: MCC-DM1 is used as an active molecule-linker coupler for ADC synthesis, e.g. for the synthesis of Anti-CD22-MCC-DM1.
BA2661 SN38-COOH

Summary: SN38-COOH can be used to synthesize antibody-activated molecule couplings (ADCs).