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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A1652 Dimesna

Summary: Uroprotective agent

insoluble in EtOH; ≥16.35 mg/mL
A5133 Irinotecan
1 Citation

Summary: Topoisomerase I inhibitor

insoluble in H2O; ≥11.4 mg/mL
A5166 Ondansetron HCl

Target: 5-HT3 Receptors

Summary: 5-HT3 receptor antagonist

insoluble in EtOH; insoluble in H2O; ≥33.04 mg/mL
A1602 Dexrazoxane HCl (ICRF-187, ADR-529)

Target: Topoisomerases

Summary: Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent

insoluble in EtOH; ≥15.24 mg/mL
A2133 Saracatinib (AZD0530)
3 Citation

Target: Src

Summary: Src/Abl inhibitor,potent and selective

≥27.1 mg/mL
A1778 Vatalanib (PTK787) 2HCl

Target: VEGFR

Summary: Tyrosine kinase receptor inhibitor

≥21 mg/mL
A5318 Prazosin HCl

Summary: α1 and α2B-adrenoceptor antagonist

insoluble in H2O; insoluble in EtOH; ≥6.99 mg/mL
A5932 Candesartan

Summary: Angiotensin II receptor 1 (AT1) antagonist

insoluble in H2O; ≥14.65 mg/mL
A8019 Perindopril Erbumine

Target: Angiotensin-Converting Enzymes (ACEs)

Summary: ACE inhibitor

≥111.4 mg/mL
A5375 Tranilast

Summary: Angiogenesis inhibitor

≥32.7 mg/mL