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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8503 Piroxicam

Target: COX|Prostaglandin synthesis

Summary: Prostaglandin synthesis/Coxinhibitor

insoluble in H2O; insoluble in EtOH; ≥16.57 mg/mL
A8621 Bestatin hydrochloride

Target: Aminopeptidases

Summary: Inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.

≥125 mg/mL
A8627 Bafilomycin A1
5 Citation

Summary: V-ATPases inhibitor

Soluble in DMSO
A8804 AMG232
2 Citation

Target: p53-MDM2 interaction

Summary: p53-MDM2 inhibitor, novel

≥53.3 mg/mL
B1524 Erastin
30 Citation

Target: Ras

Summary: ferroptosis inducer

insoluble in H2O; insoluble in EtOH; ≥10.92 mg/mL
B1645 JSH-23
5 Citation

Summary: NF-κB inhibitor

≥24 mg/mL
B1251 Valproic acid
6 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC1 inhibitor

≥12.35 mg/mL
B1210 Aniracetam

Summary: Nootropic drug for senile dementia

insoluble in H2O; ≥10.96 mg/mL
B2284 Fostamatinib (R788)
1 Citation

Target: Syk

Summary: Spleen tyrosine kinase (Syk) inhibitor

insoluble in H2O; ≥100.4 mg/mL
B2303 Apatinib
4 Citation

Summary: VEGFR2 inhibitor, orally bioavailable, selective

≥49.4 mg/mL