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Bioactive Compounds

Bioactive Compounds

A8474 Mirabegron (YM178)

Target: adrenoceptor

Summary: Selective β3-adrenoceptor agonist
A8606 PD 180970

Summary: P210bcr/abl tyrosine kinase inhibitor

<21.46 mg/mL
A8654 HPI 1

Summary: Hh signaling inhibitor

Soluble in DMSO
A8675 TRAP-6

Target: PAR

Summary: PAR1 agonist

insoluble in EtOH; ≥24.85 mg/mL
A8684 ZM 306416

Summary: VEGFR (Flt and KDR) inhibitor

≥33.4 mg/mL
A8685 Wnt-C59
2 Citation

Target: PORCN

Summary: PORCN inhibitor,highly potent and selective

.95 mg/mL

insoluble in H2O; ≥18
B1374 WZ4003
2 Citation

Target: NUAK1|NUAK2

Summary: NUAK1/2 inhibitor, potent and selective
B1408 CNX-774

Summary: BTK inhibitor, orally active, irreversible and selective

Soluble in DMSO
B1176 Y-39983 dihydrochloride

Summary: ROCK family inhibitor

≥18.05 mg/mL
B1285 SB 203580 hydrochloride

Target: p38

Summary: Specific p38-MAPKs inhibitor

insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL