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Bioactive Compounds

Bioactive Compounds

A4136 TG101348 (SAR302503)
2 Citation

Target: FLT3|JAK|c-RET

Summary: JAK-2 inhibitor,potent and selective

≥26.23 mg/mL
A4068 SNX-2112
1 Citation

Summary: Hsp90 inhibitor,ATP-competitve,potent and selective

≥23.05 mg/mL
A4074 S/GSK1349572

Summary: HIV integrase inhibitor, novel and potent

≥41.9 mg/mL
A4163 UPF 1069

Target: PARP

Summary: Selective PARP2 inhibitor

insoluble in H2O; ≥12.7 mg/mL
A4031 Telaprevir (VX-950)
1 Citation

Target: HCV NS3-4A protease

Summary: HCV NS3-4A protease inhibitor

≥32.95 mg/mL
A4095 Pracinostat (SB939)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Pan-HDAC inhibitor

insoluble in H2O; ≥11.4 mg/mL
A4119 AMG-900

Summary: Aurora kinase inhibitor

≥25.2 mg/mL
A4234 TW-37
1 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1

insoluble in H2O; ≥19.75 mg/mL
A4307 GW0742

Summary: PPARδ/β agonist,potent and selective

≥47.1 mg/mL
A4329 Cilomilast

Target: Phosphodiesterases (PDEs)

Summary: Potent PDE4 inhibitor

insoluble in H2O; ≥12.95 mg/mL