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Bioactive Compounds

Bioactive Compounds

A8252 Nintedanib (BIBF 1120)
3 Citation

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8346 BYL-719
1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A8355 Acetarsone

Summary: An organoarsenic compound

insoluble in H2O; insoluble in EtOH; ≥12.95 mg/mL
A8565 Purvalanol B
1 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK1/CDK2/CDK4 inhibitor

≥21.65 mg/mL
A8646 Trovafloxacin mesylate

Summary: Fluoroquinolone antibiotic

≥50.8 mg/mL
A9903 p53/MDM2 Set I

Summary: For inhibiting MDM2-p53 interaction
A8807 MK-8745

Target: Aurora Kinases

Summary: Aurora A inhibitor,potent and selective

≥21.6 mg/mL
B1525 SSR128129E

Summary: allosteric inhibitor of FGFR1, orally-active

insoluble in EtOH; insoluble in H2O; ≥17.3 mg/mL
B3249 Vanoxerine

Summary: potent and selective DRI (Dopamine reuptake inhibitor)

Soluble in DMSO