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Bioactive Compounds

Bioactive Compounds

B1105 AZD-9291 mesylate

Summary: third generation EGFRm inhibitor, oral and irreversible

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
B1083 LEE011 hydrochloride

Summary: CDK inhibitor

Soluble in DMSO
B2182 CAY10505

Summary: Potent PI3Kγ inhibitor

insoluble in EtOH; insoluble in H2O; ≥14.45 mg/mL
B2272 Phenytoin sodium

Target: Voltage-gated Sodium (NaV) Channels

Summary: Sodium channel stabilizer

insoluble in H2O; insoluble in EtOH; ≥11.55 mg/mL
B1344 Phenylephrine HCl

Summary: Selective α1-adrenergic receptor agonist

≥10.18 mg/mL
B3505 Diclofenac

Summary: non-selective COX inhibitor

insoluble in H2O; ≥14.81 mg/mL
B6287 Arcaine sulfate

Summary: NMDA antagonist

Soluble to 25 mM in H2O
B6460 THIP hydrochloride

Summary: GABAA receptor agonist and GABAA-ρ receptor antagonist

insoluble in EtOH; ≥23.2 mg/mL
B7756 C 21

Summary: Protein arginine methyltransferase 1 (PRMT1) inhibitor

Soluble to 2 mg/mL
B6261 (R)-3-Carboxy-4-hydroxyphenylglycine

Summary: NMDA and AMPA/kainate receptor antagonist