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Bioactive Compounds

Bioactive Compounds

A4181 EX 527 (SEN0014196)
12 Citation

Target: Sirtuin

Summary: SIRT1 inhibitor

insoluble in H2O; ≥12.43 mg/mL
A4189 IOX2(Glycine)
1 Citation

Summary: HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor

insoluble in EtOH; insoluble in H2O; ≥17.6 mg/mL
A8208 Tariquidar
6 Citation

Target: P-glycoprotein (P-gp)

Summary: P-glycoprotein inhibitor,potent and non-competitive

insoluble in H2O; insoluble in EtOH; ≥16.17 mg/mL
A1904 Boc-D-FMK
2 Citation

Target: Caspases

Summary: Pan-caspase inhibitor

insoluble in H2O; ≥11.65 mg/mL
A1908 AMI-1

Summary: PRMT1 inhibitor

insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL
A1912 Lomeguatrib

Target: O6-methylguanine-DNA-methyl-transferase (MGMT)

Summary: MGMT inhibitor

≥50 mg/mL
A4311 PF-4981517

Summary: CYP3A4 inhibitor,potent and selective

Soluble in DMSO
A4320 Voriconazole

Summary: CYP51 inhibitor

≥34.9 mg/mL
A4332 Nepicastat (SYN-117) HCl

Summary: Dopamine-β-hydroxylase inhibitor

insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
A4350 Pralatrexate

Summary: Antifolate,a folate analog

≥23.85 mg/mL