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Bioactive Compounds

Bioactive Compounds

B1523 PF-573228
5 Citation

Summary: ATP-competitive FAK inhibitor

insoluble in EtOH; insoluble in H2O; ≥166.6 mg/mL
B1530 Niflumic acid

Summary: Ca2+-activated Cl- channel blocker

insoluble in H2O; ≥12.15 mg/mL
B1650 Trimebutine

Summary: Antimuscarinic

insoluble in H2O; ≥16.2 mg/mL
A8198 P 22077

Summary: USP7/(DUB)USP47 inhibitor

insoluble in H2O; insoluble in EtOH; ≥14.6 mg/mL
A2601 Aclacinomycin A
4 Citation

Target: Topoisomerases

Summary: Topoisomerase I and II inhibitor

Soluble in DMSO
A4022 BMS-708163 (Avagacestat)

Summary: γ-secretase inhibitor

insoluble in H2O; ≥177.6 mg/mL
A4083 Rocilinostat (ACY-1215)
5 Citation

Target: Histone Deacetylases (HDACs)

Summary: Selective HDAC6 inhibitor

≥21.675 mg/mL
A4084 Vorinostat (SAHA, MK0683)
22 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
A4060 Geldanamycin
2 Citation

Summary: Hsp90 inhibitor,potent and specific

insoluble in EtOH; insoluble in H2O; ≥16.9 mg/mL
A4154 Olaparib (AZD2281, Ku-0059436)
37 Citation

Summary: PARP-1/2 inhibitor

≥21.72 mg/mL