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Bioactive Compounds

Bioactive Compounds

A4089 Mocetinostat (MGCD0103, MG0103)

4 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,isotype-selective and potent

insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
A4061 IPI-504 (Retaspimycin hydrochloride)

3 Citation

Target: HSP90

Summary: Hsp90 inhibitor,novel, potent,selective

≥26.1 mg/mL
A4156 Rucaparib (AG-014699,PF-01367338)

3 Citation

Summary: Potent PARP inhibitor

≥21.08 mg/mL
A4168 Entacapone

Target: Catechol O-Methyltransferase (COMT)

Summary: COMT inhibitor
A4113 ZM 447439

2 Citation

Target: Aurora Kinases|MEK|Src|Lck

Summary: Aurora Kinase inhibitor,potent and selective

≥25.7 mg/mL
A4037 Vildagliptin (LAF-237)

Summary: DPP-4 inhibitor

≥12.05 mg/mL
A4123 KW 2449

Target: Aurora Kinases|FLT3|Bcr-Abl

Summary: Multikinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥16.6 mg/mL
A4204 JNJ-26854165 (Serdemetan)

1 Citation

Target: p53|HDM2 ubiquitin ligase

Summary: P53 activator, blocking Mdm2-p53 interaction

insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
A4200 Apogossypolone (ApoG2)

2 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor,nonpeptidic small molecule

≥24.55 mg/mL
A4023 LY3039478

1 Citation

Target: Notch

Summary: Notch inhibitor, novel and potent

≥23.2 mg/mL