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Bioactive Compounds

Bioactive Compounds

A1835 Pelitinib (EKB-569)

Summary: EGFR inhibitor,potent and irreversible

insoluble in EtOH; insoluble in H2O; ≥11.7 mg/mL
A5413 HMN-214

Summary: Plk inhibitor,broad-spectrum anti-tumor agent

≥21.2 mg/mL
A5639 BIRB 796 (Doramapimod)
1 Citation

Summary: P38 MAPK inhibitor,cell permeable and highly selective

≥26.4 mg/mL
A2547 Vortioxetine (Lu AA21004) HBr

Summary: 5-HT receptor modulator, antidepressant and anxiolytic

insoluble in H2O; ≥50 mg/mL
A8304 FR 180204

Target: ERK

Summary: ERK inhibitor

insoluble in H2O; ≥10.25 mg/mL
A8332 R788 disodium

Target: Syk

Summary: Syk inhibitor,ATP competitive and potent

≥62.4 mg/mL
A8333 Canagliflozin
4 Citation

Target: SGLT

Summary: SGLT2 inhibitor,potent and selective

≥22.25 mg/mL
A8340 Cyclopamine
7 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
A8351 VX-809

Target: CFTR

Summary: CFTR corrector

≥22.6 mg/mL
A8435 Furosemide

Target: Na /K /Cl- Symporters (NKCCs)|GABAA Receptors

Summary: GABAA receptors antagonist