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Ruxolitinib phosphate JAK1/JAK2 inhibitor

Catalog No.A3781
Size Price Stock Qty
10mM (in 1mL DMSO)
$55.00
In stock
5mg
$70.00
In stock
25mg
$150.00
In stock
100mg
$280.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Chemical structure

Ruxolitinib phosphate

Ruxolitinib phosphate Dilution Calculator

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Ruxolitinib phosphate Molarity Calculator

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Chemical Properties

Cas No. 1092939-17-7 SDF Download SDF
Synonyms INCB018424 phosphate;INCB 018424 phosphate;INCB-018424 phosphate;Ruxolitinib
Chemical Name (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
Canonical SMILES [HH].C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OOP(=O)=O
Formula C17H21N6O4P M.Wt 404.36
Solubility >20.2mg/mL in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.