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Ruxolitinib phosphate

In stock
Catalog No.
JAK1/JAK2 inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
In stock
In stock
In stock
In stock

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INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
Cas No.1092939-17-7
SynonymsINCB018424 phosphate;INCB 018424 phosphate;INCB-018424 phosphate;Ruxolitinib
Solubility≥20.2 mg/mL in DMSO, ≥6.92 mg/mL in EtOH with ultrasonic and warming, ≥8.03 mg/mL in H2O with ultrasonic and warming
Chemical Name(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
SDFDownload SDF
Canonical SMILES[HH].C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OOP(=O)=O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Chemical structure

Ruxolitinib phosphate