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Cercosporamide

Catalog No.
A4511
Mnk2 and JAK3 inhibitor
Grouped product items
SizePriceStock Qty
500ug
$810.00
Ship with 10-15 days
1mg
$1,343.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3 (IC50 values are 11, 31 and 116 nM for Mnk2, JAK3 and Mnk1 respectively). Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro. Also inhibits Pkc1. Orally bioavailable.

Chemical Properties

Physical AppearanceA light to dark tan solid
StorageStore at -20°C
M.Wt331.28
Cas No.131436-22-1
FormulaC16H13NO7
SolubilityLimited solubility, soluble in DMSO
Chemical Name(9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
SDFDownload SDF
Canonical SMILESCC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

Cercosporamide