Anti-Bak Rabbit Polyclonal Antibody
Catalog No.
PA1042
Anti-Bak Rabbit Polyclonal Antibody
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Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.
578
BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
Rabbit
Human, Mouse
Unconjugated
Calculated MW: 23 kDa; Observed MW: 23 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Free
A synthesized peptide derived from human Bak
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.