5-Methoxy-CTP
Catalog No.
B8062
5-Methoxy-modified cytidine triphosphate for in vitro mRNA transcription synthesis
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5-Methoxy-CTP is a chemically modified cytidine triphosphate analog, characterized by a methoxy group substitution at position 5 of the cytosine ring. During in vitro transcription, it can be enzymatically incorporated into synthesized RNA, resulting in RNAs containing 5-methoxy-modified cytidine residues. This methoxy substitution influences RNA chemical properties, alters its structural characteristics, and enhances resistance against intracellular nucleolytic degradation. Consequently, 5-Methoxy-CTP is valuable for investigating RNA structural dynamics, RNA-protein interactions, and RNA functional roles, and it holds potential utility in RNA-based therapeutics, functional genomics research, and gene therapy approaches.
5-Methoxy-CTP is a modified cytidine triphosphate (CTP) containing a methoxy group at the 5 position of the cytosine ring. This modification significantly alters the chemical properties and biological functions of the nucleotide. During in vitro mRNA synthesis, 5-Methoxy-CTP can be incorporated into RNA molecules to generate RNA that contains 5-methoxycytidine. Such methoxy modifications play an essential role in studying RNA structure, function, and its interactions with proteins. Additionally, 5-Methoxy-CTP notably improves RNA stability and reduces RNA degradation within cells. Thus, this modification finds extensive applications in gene expression research, RNA-based drug development, and gene therapy.
lithium (5-(4-amino-5-methoxy-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate
C10H18N3O15P3 (free acid)
Store at -20°C or below