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VEGF165, human recombinant protein

Catalog No.
P1041
VEGF165, vascular permeability factor, expressed in E.Coli.
Grouped product items
SizePriceStock Qty
10ug
$251.00
Ship with 5-10 days
50ug
$785.00
Ship with 5-10 days
1mg
$4,752.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Vascular Endothelial Growth Factor (VEGF), also known as vascular permeability factor, is a potent growth and angiogenic cytokine produced in vascularized tissues. VEGF is a potent mediator of both angiogenesis and vasculogenesis, and stimulates proliferation and survival of endothelial cells. VEGF signals through the three receptors: fms-like tyrosine kinase (flt-1), KDR  and flt4. VEGF induces angiogenesis, vasculogenesis and endothelial cell growth, mediates increased vascular permeability, promotes cell migration, and inhibits apoptosis.

Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length. VEGF165 is the most abundant and potent isoform. Recombinant human VEGF is a 38.2 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.

Biological Activity

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-7.0 ng/ml.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:< 0.1 ng/μg

Related Biological Data

FGF-21
 

Description

Gene ID: 7422 Accession #: Q96KJ0
Alternate Names:Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen.
Source: Escherichia Coli. M.Wt: 38.2 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Sterile filtered and lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week and -20°C for future use.
Shipping Condition: Blue ice. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.