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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
VAL-083 is a bi-functional alkylating agent, with potential antitumor activity.
VAL-083 can cross the blood brain barrier and appears to be selective for tumor cells. VAL-083 alkylates and crosslinks DNA which ultimately inhibit the proliferation of cancer cells. VAL-083 does not show cross-resistance to other conventional chemotherapeutic agents. The half-life of VAL-083 in the brain is long. VAL-083 has been assessed in multiple studies as chemotherapy in the treatment of newly diagnosed and recurrent brain tumors.
Reference:http://www. delmarpharma.com/product_development_programs/val083/