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Thymidine

In stock
Catalog No.
C3486
pyrimidine nucleoside
Grouped product items
SizePriceStock Qty
5g
$55.00
In stock
10g
$97.00
In stock
25g
$172.00
In stock

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Background

Thymidine, also named as deoxythymidine, deoxyribosylthymine and thymine deoxyriboside, is a pyrimidine deoxynucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. Thymidine is the DNA nucleoside T paired with deoxyadenosine (A) in DNA double helix. In cell biology it has been used to synchronize the cells in G1/early S phase. Thymidine occurs almost exclusively in DNA but it also occurs in the T-loop of tRNA. Thymidine is non-toxic and as part of one of the four nucleosides in DNA it is a naturally occurring compound existed in organisms and DNA viruses [1]. Thymidine is a nucleoside composed of a pentose sugar, deoxyribose, and a pyrimidine base thymine. Phosphorylation of thymidine with one, two or three phosphoric acid groups, can form dTMP (deoxythymidine monophosphate), dTDP, or dTTP. The molecular weight of thymidine is 242.229 u. The melting point is 185°C.

Reference:
[1] Meng S, Maragakis P, Papaloukas C, et al.  DNA nucleoside interaction and identification with carbon nanotubes[J]. nano letters, 2007, 7(1): 45-50.

Chemical Properties

StorageStore at RT
M.Wt242.2
Cas No.50-89-5
FormulaC10H14N2O5
Synonyms2’-deoxy Thymidine,2’-deoxy-5-methyl-Uridine,5-Methyldeoxyuridine,NSC 21548,Thymine deoxyriboside
Solubility≥24.2mg/mL in DMSO with gentle warming, ≥53.6 mg/mL in H2O, ≥3.75 mg/mL in EtOH with ultrasonic
Chemical Name(8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
SDFDownload SDF
Canonical SMILESCC1=CN([[email protected]@H]2O[[email protected]](CO)[[email protected]@H](O)C2)C(NC1=O)=O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

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