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Sulfo-NHS-SS-11-Biotin

Catalog No.
A8015
Amine-reactive biotinylation reagent, mid-length
Grouped product items
SizePriceStock Qty
100mg
$95.00
In stock
1g
$700.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Sulfo-NHS-SS-11-biotin is a long-chain cleavable amine-reactive biotinylation reagent. The presence of the negatively charged sulfonate group in the chemical structure of sulfo-NHS-SS-11-biotin makes it a water-soluble biotinylation reagent that can be directly added to aqueous reactions without prior dissolution of organic solvents. Although no prior dissolution is required, an aqueous stock solution of sulfo-NHS-SS-11-biotin must be prepared rapidly and used immediately in case of the occurrence of hydrolysis of the active ester. Sulfo-NHS-SS-11-biotin has been used to react with amine-containing proteins and other molecules forming a complex which further interacts with avidin or streptavidin probes and to purify targeted molecules using affinity chromatography on a column of immobilized avidin or streptavidin.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt677.77
FormulaC22H32N5NaO10S4
Solubilityinsoluble in EtOH; ≥48.9 mg/mL in H2O; ≥49.2 mg/mL in DMSO
Chemical Namesodium 2,5-dioxo-1-((3-((3-oxo-3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)propyl)disulfanyl)propanoyl)oxy)pyrrolidine-3-sulfonate
SDFDownload SDF
Canonical SMILESO=C1N[[email protected]]2([H])[[email protected]]([[email protected]](CCCCC(NCCNC(CCSSCCC(ON3C(CC(S(=O)(O[Na])=O)C3=O)=O)=O)=O)=O)SC2)([H])N1
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

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