Sulfanilamide
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 172.2 |
| Cas No. | 63-74-1 |
| Formula | C6H8N2O2S |
| Solubility | ≥7.7mg/mL in DMSO |
| Chemical Name | 4-aminobenzenesulfonamide |
| SDF | Download SDF |
| Canonical SMILES | C1=CC(=CC=C1N)S(=O)(=O)N |
| Shipping Condition | Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request. |
| General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months. |
| Cell experiment [1]: | |
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Cell lines |
Plasmodium falciparum |
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Preparation method |
The solubility of this compound in DMSO is ≥7.7 mg/mL. General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months. |
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Reacting condition |
380 uM |
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Applications |
Sulfanilamide moderately inhibits the Plasmodium falciparum growth. |
| Animal experiment [1]: | |
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Animal models |
Male, immunosuppressed Sprague-Dawley rats |
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Dosage form |
100, 10, and 1.0 mg/kg/day |
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Application |
Sulfanilamide effectively inhibited P.carinii infection in immunosuppressed rat model with a concentration of 100.0 mg/kg /day. When the dose of Sulfanilamide was reduced to 10.0 mg/kg/day, P. carinii infection occurred. |
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Other notes |
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal. |
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References: [1]. Kasekarn W, Sirawaraporn R, Chahomchuen T, Cowman AF, Sirawaraporn W. Molecular characterization of bifunctional hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase from Plasmodium falciparum. Mol Biochem Parasitol. 2004 Sep;137(1):43-53. PubMed PMID: 15279950. [2]. Hughes WT, Killmar J. Monodrug efficacies of sulfonamides in prophylaxis for Pneumocystis carinii pneumonia. Antimicrob Agents Chemother. 1996 Apr;40(4):962-5. PubMed PMID: 8849260; PubMed Central PMCID: PMC163239. |
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Quality Control & MSDS
- View current batch:
Chemical structure
