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Semaxanib (SU5416)

Catalog No.
B2304
VEGFR(Flk-1/KDR) inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$140.00
In stock
Evaluation Sample
$28.00
In stock
5mg
$119.00
In stock
10mg
$189.00
In stock
50mg
$679.00
In stock
100mg
$889.00
In stock

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Background

Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt238.28
Cas No.194413-58-6
FormulaC15H14N2O
Solubility≥11.9mg/mL in DMSO
Chemical Name(3E)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
SDFDownload SDF
Canonical SMILESCC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

Semaxanib (SU5416)