IκB/IKK

IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.

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product-structure

Cat.No. Product Name Information
B5638 ACHP IκB kinase inhibitor
N1855 Andrographolide NF-κB signaling Inhibitor
B3033 Bay 11-7085 NK-κB activation inhibitor
A4210 Bay 11-7821(BAY 11-7082) IKK/NF-κB/TNFα inhibitor
A3230 Bay 65-1942 HCl salt IKKβ kinase inhibitor
B4655 BMS-345541(free base) IKK-1/IKK-2 inhibitor,potent and selective
A3248 BMS345541 hydrochloride IKK inhibitor,highly selective
A2604 Celastrol Antioxidant, anti-inflammatory and immunosuppressive agent
A3308 Choline Fenofibrate Choline salt of fenofibric acid
A3311 CID-2858522 NF-κB pathway inhibitor

Product Name	IKK-1/IKKα	IKK-2/IKKβ	IKK complex	IKK-ε	Other Targets
IMD 0354		*
IKK-16 (IKK Inhibitor VII)	**	***	***
TPCA-1	**	***
IKK-3 Inhibitor				***
Bay 65-1942 free base		*
Bay 65-1942 HCl salt		*
Bay 65-1942 R form		****
PF 184		***
ACHP	**	****
PS 1145 dihydrochloride			***
ML 120B dihydrochloride		***
IKKε-IN-1				***
MRT67307				**	MARK1-4 NUAK1 ULK1/2 SIK1/2/3
MLN120B		*
IKK-2 inhibitor VIII		****
BMS-345541	*	**
SC-514		*			CDK2/CyclinA AUR2 PRAK p38α
Withaferin A		*			20S proteasome