Pyrimethamine
Catalog No.
A4353
DHFR inhibitor
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Pyrimethamine is a dihydrofolate reductase(DHFR) inhibitor with an IC50 of 15.4 nM.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 248.71 |
| Cas No. | 58-14-0 |
| Formula | C12H13ClN4 |
| Solubility | insoluble in H2O; ≥10 mg/mL in DMSO with gentle warming; ≥5.23 mg/mL in EtOH with ultrasonic |
| Chemical Name | 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |
| SDF | Download SDF |
| Canonical SMILES | CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl |
| Shipping Condition | Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request. |
| General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months. |
Quality Control & MSDS
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Chemical structure
