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PDGF-AA, murine recombinant protein

Catalog No.
P1046
PDGF-AA, platelet-derived growth factor, expressed in E.Coli.
Grouped product items
SizePriceStock Qty
10ug
$251.00
Ship with 5-10 days
1mg
$6,138.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

The platelet-derived growth factor AA (PDGF-AA) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). The PDGFs are stored in platelet α-granules, and are released upon platelet activation. PDGFs signals through receptors PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. However, PDGFR-β interacts with only PDGF-BB and PDGF-AB. PDGF-AA is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells and some blood cells.

Recombinant mouse PDGF-AA is a disulfide linked non-glycosylated homodimer comprised of 2 polypeptide chains of 126 amino acids each, with a dimeric molecular weight of 28.9 kDa.

Biological Activity

Determined by the dose-dependent proliferation of Balb/c 3T3 cells and is typically 8 -10 ng/ml.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥97%, by SDS-PAGE and HPLC.
    Endotoxin Level:< 0.01 ng/μg/span>

Related Biological Data

FGF-21
 

Description

Gene ID: 18590 Accession #: P20033
Alternate Names:PDGFA, Mouse PDGF-AA, h-PDGF-AA, PDGFAA, PDGF AA, PDGF-AA, rh-PDGF-AA, recombinant mouse PDGF-AA, recombinant PDGF-AA, PDGF.
Source: Escherichia Coli. M.Wt: 28.9 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-0.5 mg/ml. This solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week and -20°C for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.