Toggle Nav
Close
  • Menu
  • Setting

NPS-2143 hydrochloride

Catalog No.
A3667
Calcium ion-sensing receptor antagonist
Grouped product items
SizePriceStock Qty
5mg
$60.00
In stock
10mg
$85.00
In stock
50mg
$320.00
In stock
200mg
$930.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

NPS-2143 is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.NPS-2143 is useful for treatment of osteoporosis;

Chemical Properties

StorageStore at -20°C
M.Wt445.38
Cas No.324523-20-8
FormulaC24H26Cl2N2O2
SynonymsNPS2143 hydrochloride;NPS 2143 hydrochloride
Solubility≥44.5 mg/mL in DMSO, ≥11.43 mg/mL in EtOH with ultrasonic and warming,insoluble in H2O
Chemical Name2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile;hydrochloride
SDFDownload SDF
Canonical SMILESCC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control