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NB-598

Catalog No.
A3645
SE inhibitor
Grouped product items
SizePriceStock Qty
5mg
$246.00
In stock
10mg
$339.00
In stock
50mg
$986.00
In stock
200mg
$2,262.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

Chemical Properties

Physical AppearanceA brown oil
StorageStore at -20°C
M.Wt449.67
Cas No.131060-14-5
FormulaC27H31NOS2
SynonymsNB 598;NB598
SolubilitySoluble in DMSO
Chemical Name(E)-N-(3-([3,3'-bithiophen]-5-ylmethoxy)benzyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine
SDFDownload SDF
Canonical SMILESCCN(CC1=CC(OCC2=CC(C3=CSC=C3)=CS2)=CC=C1)C/C=C/C#CC(C)(C)C
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

NB-598