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Lurasidone HCl

Catalog No.
Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor
Grouped product items
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In stock
In stock

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Lurasidone Hcl (SM 13496 Hcl) is an inhibitor of Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively, which is an atypical antipsychotic.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
Cas No.367514-88-3
Solubilityinsoluble in H2O; insoluble in EtOH; ≥11.11 mg/mL in DMSO with gentle warming
Chemical Name(3aR,4R,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride
SDFDownload SDF
Canonical SMILESCl[H].O=C(C1([H])[[email protected]](C([H])([H])C2([H])[H])([H])C([H])([H])C2([H])C13[H])N(C([H])([H])C4([H])C(C([H])([H])N5C([H])([H])C([H])([H])N(C6=NSC7=C6C([H])=C([H])C([H])=C7[H])C([H])([H])C5([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C3=O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

Lurasidone HCl