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APExBIO

Hexa His tag peptide

In stock
Catalog No.
A6006
Synthetic 6XHis peptide
Grouped product items
SizePriceStock Qty
5mg
$129.00
In stock
25mg
$518.00
In stock

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Hexa His is an amino acid sequence consisting of 6 His residues in a row, it is also known as hexa histidine-tag, 6xHis-tag, and by the trademarked name His-tag. Hexa His Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. Hexa His acts as a metal binding site for a recombinant protein. His-Tag sequence can be placed on the N- or -terminal of a target protein by using vectors from various commercial molecular biology companies. And this Tag is often followed by a cleavage site for a specific protease - for example Leu-Val-Arg-Gly-Ser peptide sequence is recognized and cleaved by the protease known as thrombin.

References:
1.  Hengen, P (1995). "Purification of His-Tag fusion proteins from Escherichia coli". Trends in Biochemical Sciences 20 (7): 285–6.

Product Citation

Chemical Properties

StorageDesiccate at -20°C
M.Wt840.85
FormulaC36H44N18O7
SynonymsH-His-His-His-His-His-His-OH
Solubility≥84.1mg/mL in DMSO
Chemical NameHexa His
SDFDownload SDF
Canonical SMILESC1=C(NN=C1)CC(C(=O)NC(CC2=CC=NN2)C(=O)NC(CC3=CC=NN3)C(=O)NC(CC4=CC=NN4)C(=O)NC(CC5=CC=NN5)C(=O)NC(CC6=CC=NN6)C(=O)O)N
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Biological Activity

Description Hexa His tag peptide is a 6 x His tag used as a metal binding site for the recombinant protein.
Targets anti-6 x His tag antibody          
IC50            

Quality Control

Chemical structure

Hexa His tag peptide

Related Biological Data

Hexa His tag peptide

Related Biological Data

Hexa His tag peptide

Related Biological Data

Hexa His tag peptide